Plasma N-Terminal B-Type Natriuretic Peptide as an Indicator of Long-Term Survival After Acute Myocardial Infarction: Comparison With Plasma Midregional Pro-Atrial Natriuretic Peptide
نویسندگان
چکیده
Results Plasma MR-proANP was raised in patients who died (n 101) compared with that seen in survivors (median 310 [range 48 to 1,150] pmol/l vs. 108 [range 4.9 to 1,210] pmol/l, p 0.0001). Using Cox modeling, log10MR-proANP (hazard ratio 3.87) and log10NT-proBNP (hazard ratio 3.25) were significant independent predictors of death. In patients stratified by NT-proBNP in the highest quartile ( 5,900 pmol/l), MR-proANP in the top quartile ( 330 pmol/l) was associated with poorer outcome (p 0.0001). Findings were similar for heart failure as an individual end point. However, neither marker predicted recurrent AMI.
منابع مشابه
Plasma N-terminal B type natriuretic peptide as an Indicator of Long-term Survival After Acute Myocardial Infarction: Comparison With Plasma Mid-regional Pro-atrial Natriuretic Peptide - Leicester Acute Myocardial Infarction Peptide (LAMP) Study
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تاریخ انتشار 2008